by Jason Fairchild | Sep 29, 2020 | Uncategorized
Mechanistic links between sleep, circadian regulation and risk of type 2 diabetes The Saxena laboratory studies the mechanisms by which variation in sleep and circadian pathway genes leads to increased risk for type 2 diabetes in humans. Through genome-wide...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
My research program is on the neural circuits that control basic life functions, including sleep-wake, circadian rhythms, thermoregulation, feeding and metabolism, and stress. In particular, we have identified circuits in the brain controlling circadian rhythms...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Mechanisms and novel therapeutic targets in heart failure Research in the Rosenzweig laboratory is primarily focused on heart failure because it represents both a growing unmet clinical need and an opportunity to study fundamental biological processes including...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Control of Nutrient and Energy Metabolism Nutrient Sensing and Diabetes Mamalian cells sense nutrients signals to reprogram energetic metabolism and trigger tissue specific responses within the context of whole animal physiology. For example, nutrient fluctuations...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Vitamin D and the Prevention of type 2 diabetes The program focuses on the role of vitamin D in prevention and treatment of type 2 diabetes (vitamindfordiabetes.org). The program is funded by NIH and ADA to conduct observational and randomized trials on prevention of...
