by Jason Fairchild | May 6, 2024
The overarching theme in the Perissi Lab is dissecting the molecular mechanisms that control metabolic adaptation in response to nutrients availability, cell differentiation and oxidative stress. Current projects focus on two main areas: 1) Mechanisms regulating...
by Jason Fairchild | May 6, 2024
Adipocytes, skeletal myocytes and some neurons express a specific isoform of the glucose transporter protein, Glut4. Under basal conditions this transporter is localized in intracellular membrane vesicles which fuse with the plasma membrane upon insulin...
by Jason Fairchild | May 6, 2024
The Hamburg laboratory focuses on understanding the development and clinical relevance of vascular dysfunction in patients with type 2 diabetes and obesity. The lab uses translational research approaches that combine the measurement of vascular function in patients...
by Jason Fairchild | May 6, 2024
The Dooms laboratory focuses on understanding how autoreactive, islet-specific T cells, which are present in healthy people without causing harm, acquire their pathogenic functions and cause Type 1 Diabetes (T1D) when present in genetically susceptible individuals....
