Qin Yang, MD, PhD

Regulation of Insulin Sensitivity by Adipose Tissue Research in our laboratory is focused on elucidating the mechanisms for insulin resistance and energy dysregulation in obesity and type 2 diabetes. In particular, we are investigating how adipocytes regulate systemic...

Ramnik Xavier, M.D., Ph.D

Systems biology approaches to understand human disease signaling networks  The overall goal in the laboratory is to discover and understand the function of important mediators and effectors involved in innate (autophagy, phagocytosis) and adaptive (T cell...

Gordon Williams, M.D.

Genetic Underpinnings of Hormonal Mechanisms Contributing to Cardiovascular Risk in Diabetes Mellitus For the past 20 years, we have studied the genetic underpinnings of hormonal factors leading to HTN and its associated CV risks.  From these studies, we have...

Corrine Welt-Kolka, MD

The Genetics of Polycystic Ovary Syndrome Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive aged women. Its health threatening consequences include a very high rate of type 2 diabetes, impaired glucose tolerance and metabolic...

Bridget Wagner, PhD

High throughput methods to identify beta cell modulators Beta-cell death, and the consequent deficiency in insulin secretion, is a key feature of type 1 diabetes. For decades, the standard of care for this disease has been insulin therapy by intramuscular injection....