Alex Soukas, M.D., PhD

Diabetes and Obesity Genetics in C. elegans and Mice   Fat regulatory gene discovery in C. elegans. The lab uses the soil roundworm C. elegans in large-scale gene discovery screens to uncover and characterize genetic pathways involved in storage and...

Guo-Ping Shi, ScD.

Inflammation in obesity and diabetes Accumulating evidence suggests that inflammatory cells, including macrophages, different subtypes of T cells, neutrophils, eosinophils, and mast cells all contribute to the development and progression of obesity and diabetes (1-7)....

Richa Saxena, PhD

Mechanistic links between sleep, circadian regulation and risk of type 2 diabetes The Saxena laboratory studies the mechanisms by which variation in sleep and circadian pathway genes leads to increased risk for type 2 diabetes in humans.  Through genome-wide...

Clifford B. Saper, MD PhD

My research program is on the neural circuits that control basic life functions, including sleep-wake, circadian rhythms, thermoregulation, feeding and metabolism, and stress.  In particular, we have identified circuits in the brain controlling circadian rhythms...

Anthony Rosenzweig, M.D.

Mechanisms and novel therapeutic targets in heart failure Research in the Rosenzweig laboratory is primarily focused on heart failure because it represents both a growing unmet clinical need and an opportunity to study fundamental biological processes including...