Bruce Spiegelman, PhD

Bruce Spiegelman, PhD

Our lab is focused on the regulation of energy homeostasis in mammals, primarily at the level of gene transcription. This includes the problems of fat cell development, control of metabolic rates and the pathways of glucose and lipid metabolism. These studies have...
Bruce Spiegelman, PhD

Pere Puigserver, PhD

Nutrient Sensing and Diabetes: Mammalian cells sense nutrients signals to reprogram energetic metabolism and trigger tissue specific responses within the context of whole animal physiology. For example, nutrient fluctuations during fed/fasting or diabetic conditions...