by Jason Fairchild | May 6, 2024
Broadly, my laboratory seeks to utilize next generation sequencing technologies and analysis to better understand the genetic, epigenetic, and tissue/cell type bases of metabolic disease. In particular, we study the biological and neural circuits and gene regulatory...
by Jason Fairchild | May 6, 2024
The Saper laboratory works on neural circuitry that underlies several basic and related hypothalamic functions, including circadian rhythms; wake-sleep cycles; thermoregulation; and feeding and metabolic control. We study brain circuitry that regulates these functions...
by Jason Fairchild | May 6, 2024
The Rosen lab strives to understand how gene expression networks control the development, function, and pathophysiology of metabolically relevant tissues, with an emphasis on adipose tissue. We employ genetic, genomic, computational, cell biological, and in vivo...
by Jason Fairchild | May 6, 2024
We utilize genetic engineering techniques in mice, electrophysiology, optogenetics, chemogenetics, rabies mapping, ChR2-assisted circuit mapping, in vivo assessments of neuronal activity, and single neuron transcriptomics to elucidate neural circuits controlling...
by Jason Fairchild | May 6, 2024
Identifying ROCK1 as a novel regulator of insulin signaling, glucose homeostasis, and lipogenesis: My works suggested that Rho-kinase positively regulates insulin-stimulated glucose transport and signaling via either IRS-1 serine phosphorylation or active...
