by Jason Fairchild | Sep 29, 2020 | Uncategorized
I direct a robust research program focused on dissecting the molecular mechanisms that control adaptive responses to metabolic stress and pro-inflammatory signals in adipose tissue, immune cells and breast cancer. To achieve this goal, we use a combination of basic...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
The neuroendocrine control of reproductive function and metabolism. My expertise lies in the central control of endocrine events, with special attention to the neuroendocrine regulation of energy balance and reproductive function. In this general context, the outcome...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Clinical Research in Type 1 and Type 2 Diabetes David Nathan, M.D. Dr. Nathan directs the MGH Diabetes Clinical Research Center, which focuses on the development and evaluation of innovative therapies for Type 1 and Type 2 diabetes and their complications. The...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
The histone deacetylase SIRT6 mediates crosstalk between epigenetics and metabolism Our lab is interested in understanding the influence of chromatin on DNA repair, and the relationship between the DNA damage response and the metabolic adaptation of cells. We focus on...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Systems Approaches to Metabolism and Mitochondrial Biology The research program is aimed at utilizing the new tools of genomics and computational biology to understand mitochondrial biology and metabolism. We are particularly interested in the rare mitochondrial...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Bioengineering and engraftment of microvascular networks Our laboratory is interested in understanding how vascular networks are formed and the mechanisms by which vascular networks engraftment occurs upon transplantation. Every year, millions of grafting procedures...
