by Jason Fairchild | Sep 29, 2020 | Uncategorized
Type I diabetes-Autoimmunity and Islet Regeneration Dr. Faustman’s current research program investigates human and murine Type I diabetes. She specifically investigates immunologic and genetic derangements as they relate to phenotypes of disease expression. In 1991,...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Epigenomic and Transcriptional Analysis of Adipocyte Biology Our laboratory is interested in the biology of the adipocyte in health and disease. Many projects within the lab are centered on the idea that understanding the transcriptional pathways by which...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Central regulation of food intake and energy expenditure Food-seeking behavior is driven by the interplay of internal state and cues from the external world; while remarkable progress has been made in understanding the neuroendocrinological mechanisms that translate...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
Novel signaling pathways in metabolic disease associated cardiac remodeling Our laboratory studies the interaction between acquired heart diseases and cardiac remodeling. One focus of the lab is on how kinases and other signaling pathways that are altered in...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
The role of KIM-1-mediated proximal tubule injury in the pathogenesis of diabetic nephropathy Increasing evidence suggests that the kidney tubule plays an important role, and that tubulointerstitial injury may contribute to glomerular changes in diabetes (1). We have...
by Jason Fairchild | Sep 29, 2020 | Uncategorized
The Molecular Basis of Integrin Function A major research focus of my laboratory is the dissection of the role of leukocyte integrins in inflammation, and an elucidation of the mechanisms that regulate the functions of these adhesion receptors in health and disease....
